Everyone talks about growing cloned hearts and livers like swapping car parts. I am a cardiothoracic surgeon. If you put a lab-grown 20-year-old heart with maximum pump efficiency into a 100-year-old calcified aorta, the hemodynamic mismatch will blow out the descending aorta in 24 hours. Aortic dissection is inevitable. You cannot upgrade the pump without upgrading the pipes.
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